Clinical Trials Physician

Invicro-London is a unique clinical imaging centre based at the Hammersmith Hospital Campus in West London. This facility operates state-of-the-art imaging technology in support of medical and pharmaceutical research, and is internationally renowned for its expertise in these fields.

This is an exciting role for a Clinical Trials Physician to join a dynamic Clinical Applications team at Invicro in London.

 

The role

The Clinical Trials Physician is responsible for ensuring appropriate medical care is provided for study participants, during study conduct, and follow-up, and will have specific responsibility for management and governance for clinical studies conducted by Invicro London. The role is responsible for specific study-related medical decisions and activities during the course of such studies, and will support the design and conduct.

The Clinical Trials Physician is responsible for ensuring that all study related compounds and investigational medicinal products are dispensed according to regulatory and GMP requirements. Will also maintain accurate records, and updating relevant documentation as required by ICH-GCP.

 

Key Responsibilities

  • Ensure all studies are conducted in compliance with the protocol, GCP, GMP, SOP’s IRB/ethics committee and regulatory authorises.
  • Review all study specific documentation prior to initiation (including but not limited to certificate of analysis forms prior to study start, randomization codes (for un-blinded studies), reconciliation of drug accountability forms upon study completion, destroy/dispose of drugs in accordance to the study protocol and local SOPs).
  • Assume the role and responsibilities of Principal Investigator, whenever appropriate, and provide overall supervision and day to day management of other clinical staff and on-going studies in the unit.
  • Supervise and develop training of temporary non-Invicro clinical staff including those on training programmes and development fellowships.
  • Assist the Quality Assurance process relating to the manufacture and storage activities of CTS and to implement recommendations for corrective and preventative actions.

 

Specific Activities

  • Performs appropriate procedures, including but not limited to the; insertion or venous and radial artery cannulas, administration of study specific medication including IMP, PET radioligands and MRI contrast agents
  • Ensures all studies responsibilities are performed in compliance with the protocol, GCP, GMP, SOP’s IRB/ethics committee and regulatory authorisations.
  • Reviews all study specific documentation prior to providing clinical services.
  • Qualified and trained to assume the role and responsibilities of Study Physician and to provide overall supervision and management of studies in the centre.
  • Maintains awareness of relevant Invicro-London SOP’s

 

The successful candidate will have:

  • Medical qualification allowing direct medical responsibility for human investigations in the UK, with appropriate post-registration experience
  • Excellent technical proficiency in the cannulation of the radial artery and peripheral veins
  • Desirable:
    • Experience in the conduct of clinical pharmacology studies is desirable
    • Appreciation of the scientific basis of study design, including pharmacokinetics, human toxicology, statistics and pharmacodynamic assessment is desirable
    • Knowledge of principles of PET molecular imaging and MRI

You will be developing and maintaining good working relationships and therefore have highly competent communication skills. Excellent interpersonal skills and energy to operate in a complex organisational environment.

 

Competitive Salary & Benefits
Contributory Pension, Bonus, Private Medical Insurance, Life Assurance & Flexible Benefits options

To apply for this position please forward your CV and a covering letter detailing your relevant experience to HR at recruitment@invicro.co.uk

We ensure compliance with Data Protection laws and you can find our Privacy Notice by Clicking here.

Invicro is an equal opportunities employer and positively encourages applications from suitably qualified and eligible candidates regardless of sex, race, disability, age, sexual orientation, gender reassignment, religion or belief, marital status, or pregnancy and maternity.

 

Preclinical Laboratory Assistant

Invicro is the world’s leading translational imaging company. Based in London, Boston and New Haven, Invicro specialises in molecular and functional imaging studies to support medical and pharmaceutical research. The London site operates a unique preclinical and clinical imaging centre with state-of-the-art PET and MRI technology used to support.

We are looking for a Preclinical Laboratory Assistant who will play a key role in supporting studies and general biology team activities. This will include the evaluation and application of novel and established radioactive PET tracers using in vivo, ex vivo and in vitro techniques and methodologies. Training will be provided as part of this role.

Key Responsibilities:

  • Preparing and assisting in the conduct of preclinical studies
  • Performing regular quality control checks and setting up of equipment
  • Independently performing standard procedures during preclinical PET/CT imaging studies
  • Safe use of low level radioactively-labelled compound such as 18F, 11C, 3H and 14C.
  • Perform basic and routine laboratory procedures including preparation of buffers, cell culture, tissue homogenisation and sectioning for radioligand binding studies.
  • Maintaining accurate and current records of experimental work.
  • Using appropriate computer software packages effectively to enter and support the analysis of study data.
  • Undertaking general laboratory administration and support as required.

Qualifications:

  • BSc or equivalent, in Biology, Pharmacology, Neuroscience or related discipline.
  • Practical laboratory experience and experience of having worked in the preclinical field is essential.
  • Holds a current/or has previously held a home office personal license (modules 1-4) is advantageous.

Personal Characteristics and competencies:

Candidates must have:

  • An ability to work independently as well as part of a team.
  • An enthusiastic, self-motivated attitude and a willingness to expand technical skills.
  • An ability to learn and follow new protocols as they become relevant for different studies.
  • A desire to learn and develop knowledge/experience with in vivo and in vitro methodologies;
  • Competitive Salary & Benefits
  • Contributory Pension, Bonus, Private Medical Insurance, Life Assurance & Flexible Benefits options

To apply for this position please forward your CV and a covering letter detailing your relevant experience to HR at recruitment@invicro.co.uk.


We ensure compliance with Data Protection laws and you can find our Privacy Notice by clicking here.

Invicro is an equal opportunities employer and positively encourages applications from suitably qualified and eligible candidates regardless of sex, race, disability, age, sexual orientation, gender reassignment, religion or belief, marital status, or pregnancy and maternity.

Imanova Limited, company registered in England and Wales, with registration number 07516277, trading as Invicro.

Corporate Paralegal

Make an impact at a dynamic and growing company! Invicro seeks a talented and hard-working individual to join the London team and who will play a key role as part of the global Commercial Office. The ideal candidate for the Corporate Paralegal role will be a commercially aware individual that possesses hands-on experience reviewing and editing contracts, maintaining electronic document repositories, and supporting the legal requirements of a broad range of individuals across a variety of departments and levels of management.

Key Responsibilities:

Provide legal assistance to the Chief Legal Officer and Director of Legal Affairs for a wide variety of department requirements, including, but not limited to the following:

  • Review and edit legal documents, including, but not limited to, confidentiality agreements, basic service agreements, work orders, and change orders and other contracts.
  • Prepare and assist in the preparation of documents in regard to immigration and employment matters.
  • Prepare and assist in the preparation of documents related to intellectual property matters.
  • Assist in the management of risk management and insurance matters.
  • Assist in the management of corporate development matters.
  • Prepare, review, and maintain minutes, resolutions, written consents, and corporate organizational documents.
  • Assist with matters related to the Company’s internal and external auditors, executive and director compensation, and stock plan administration.
  • Maintain corporate minute books and corporate seals.
  • Manage the legal department’s files and maintain the electronic contract database
  • Assist with other legal matters as assigned.

 

Basic Qualifications:

  • Bachelor’s Degree and Paralegal Certification preferred
  • 5-10+ years in-house paralegal experience or equivalent
  • Highly skilled in standard office software (MS Office, Excel, PowerPoint, etc.)
  • Experience with third-party document management systems
  • Ability to work independently and to successfully meet deadlines
  • Excellent attention to detail
  • Excellent communication (verbal and written) and interpersonal skills
  • An effective approach to team working

 

Competitive Salary & Benefits

Contributory Pension, Bonus, Private Medical Insurance, Life Assurance & Flexible Benefits options

To apply for this position please forward your CV and a covering letter detailing your relevant experience to HR at recruitment@invicro.co.uk.


We ensure compliance with Data Protection laws and you can find our Privacy Notice by clicking here.

Invicro is an equal opportunities employer and positively encourages applications from suitably qualified and eligible candidates regardless of sex, race, disability, age, sexual orientation, gender reassignment, religion or belief, marital status, or pregnancy and maternity.

Imanova Limited, company registered in England and Wales, with registration number 07516277, trading as Invicro.

 

Analytical Chemist

To apply for this position please forward your CV and a covering letter detailing your relevant experience to recruitment@invicro.co.uk

We ensure compliance with Data Protection laws and you can find our Privacy Notice by clicking here.

This is an exciting opportunity to work in a growing life sciences company that provides medical imaging and services and software to the  drug development community. This role will be located on the Imperial College campus at Hammersmith Hospital in West London.

The Candidate:

We are seeking an Analytical Chemist, to perform QC method development and routine analysis of P.E.T. radiotracers to support clinical and pre-clinical studies in a GMP environment.  The candidate will be responsible for the following:

  • QC of radiotracers as assigned according to project distribution and the scanning schedule.
  • QC implementation of new assigned radiotracers: method development, validation and documentation.
  • Performing routine QC to support clinical and pre-clinical studies.
  • Providing analytical chemistry support for precursor characterization, radiotracer and radioligand purification.
  • Data processing including but not limited to HPLC, Ion Chromatography and GC. Knowledge of NMR and gamma spectroscopy is desirable.

To be considered for this position you will have:

  • BSc/Msc or equivalent in relevant field such as analytical chemistry or pharmaceutics
  • Experience of working analytical laboratory experience such as HPLC, TLC and GC, including method development and validation.
  • Experience with short-lived radioisotopes preferable (especially carbon-11 and fluorine-18).
  • Knowledge and practical experience of analytical chemistry techniques including but not limited to: HPLC, IC and GC.
  • Knowledge of bioanalytical techniques such as ELISA, BCA and SDS-Page is desirable.
  • Good understanding of GMP.
  • Computer literacy: competent in the use of a number of applications, including elements of the Microsoft Office suite, Internet and email software. Also conversant with industry-level database systems and analytical software such as Agilent Chemstation.
  • Ability to accomplish multiple tasks in fast-paced environment.
  • Excellent verbal and written communication skills.
  • Analytical skills and a logical approach to problem solving and an attention to detail.

Competitive Salary & Benefits

Contributory Pension, Bonus, Private Medical Insurance, Life Assurance & Flexible Benefits options

To apply for this position please forward your CV and a covering letter detailing your relevant experience to HR at recruitment@invicro.co.uk.


We ensure compliance with Data Protection laws and you can find our Privacy Notice by clicking here.

Invicro is an equal opportunities employer and positively encourages applications from suitably qualified and eligible candidates regardless of sex, race, disability, age, sexual orientation, gender reassignment, religion or belief, marital status, or pregnancy and maternity.

Imanova Limited, company registered in England and Wales, with registration number 07516277, trading as Invicro.

MRI Research Radiographer

12 Months Fixed Term

Invicro is the world’s leading translational imaging company, based in London, Boston and New Haven. Invicro specializes in molecular and functional imaging studies to support medical and pharmaceutical research. The London site operates a unique clinical and pre-clinical imaging centre with state-of-the-art PET and MRI technology, used to support clinical research.

We are seeking a dynamic, hardworking, and meticulous MRI Radiographer to join our team and assist in the day-to-day operation of our MRI imaging suite, which includes two 3 Tesla Siemens scanners and 3 Tesla GE PET-MR. The role will be to support all activities relating to Imaging and Experimental Medicine Studies in accordance with current Regulatory ICH GCP standards and requirements.

The Candidate:

The successful candidate must be registered with the Health and Care Professions Council and have a relevant Radiography qualification.

Specific Experience Required:

  • Experience in MRI scanning is essential
  • Experience in carrying out research MRI scans would be advantageous.
  • Candidates will need to demonstrate the ability to make effective decisions under pressure
  • Ideally have a working knowledge of the research environment. The contracted working hours are 37.5 hours per week and we seek candidates who have the flexibility to work the hours required to meet operational needs.

Competitive Salary & Benefits

Contributory Pension, Bonus, Private Medical Insurance, Life Assurance & Flexible Benefits options

To apply for this position please forward your CV and a covering letter detailing your relevant experience to HR at recruitment@invicro.co.uk.


We ensure compliance with Data Protection laws and you can find our Privacy Notice by clicking here.

Invicro is an equal opportunities employer and positively encourages applications from suitably qualified and eligible candidates regardless of sex, race, disability, age, sexual orientation, gender reassignment, religion or belief, marital status, or pregnancy and maternity.

Imanova Limited, company registered in England and Wales, with registration number 07516277, trading as Invicro.

Senior Study Coordinator

Invicro is the world’s leading translational imaging company. Based in London, Boston and New Haven. Invicro specialises in molecular and functional imaging studies to support medical and pharmaceutical research. The London site operates a unique clinical and pre-clinical imagining centre with state-of-the-art PET and MRI technology used to support clinical research.

We are seeking a candidate with proven skills and experience in study co-ordination to work as part of the clinical support team to complete activities relating to Imaging and Experimental Medicine Studies in accordance with current Regulatory, ICH GCP and HBSM standards and requirements.

The successful candidate must have a relevant nursing qualification and be registered with the Nursing and Midwifery Council. The post-holder will need experience in a senior clinical research role and industry based experience would be an advantage. A minimum level of ILS resuscitation training is required and the applicant should be competent in use of emergency equipment.

Applicants will need to demonstrate the ability to make effective decisions under pressure, organise and prioritise workload and communicate at a high level across multiple disciplines. We seek candidates who are adaptable and show flexibility with working patterns to support operational requirements.

Competitive Salary & Benefits

Contributory Pension, Bonus, Private Medical Insurance, Life Assurance & Flexible Benefits options

To apply for this position please forward your CV and a covering letter detailing your relevant experience to HR at recruitment@invicro.co.uk.


We ensure compliance with Data Protection laws and you can find our Privacy Notice by clicking here.

Invicro is an equal opportunities employer and positively encourages applications from suitably qualified and eligible candidates regardless of sex, race, disability, age, sexual orientation, gender reassignment, religion or belief, marital status, or pregnancy and maternity.

Imanova Limited, company registered in England and Wales, with registration number 07516277, trading as Invicro.

Quality Systems Coordinator

Invicro is the world’s leading translational imaging company.  Based in London, Boston and New Haven.  Invicro specialises in molecular and functional imaging studies to support medical and pharmaceutical research.  The London site operates a unique clinical and pre-clinical imagining centre with state-of-the-art PET and MRI technology used to support clinical research.

The Candidate

We are seeking a candidate who will be responsible for the operation of the Quality Management System supporting GMP and GCP operations within Invicro London.

The role reports to the Head of Quality & Compliance and includes administration of the system and the provision of support and training for system users.  The role also includes other QA activities related primarily to GMP manufacture, including coordination of controlled documents, involvement in internal and external audits, and preparation and reporting of Quality Metrics as part of the Management Review process.

To be considered for this position you will have:

  • Significant relevant experience, gained within the pharmaceutical or healthcare industry
  • Demonstrated knowledge, interpretation and application of quality management within a GMP environment.
  • Experience of the Q-Pulse Quality Management System (desirable)
  • Proven understanding of the requirements of GMP as they relate to documentation and Quality Systems
  • Proven ability to work across functional interfaces.
  • Strong interpersonal, communication and negotiation skills
  • Operates with minimal supervision with a proactive approach
  • Proven planning and organisation skills
  • Proven ability to work within a team environment
  • Competitive Salary & Benefits
  • Contributory Pension, Bonus, Private Medical Insurance, Life Assurance & Flexible Benefits options

To apply for this position please forward your CV and a covering letter detailing your relevant experience to HR at recruitment@invicro.co.uk.


We ensure compliance with Data Protection laws and you can find our Privacy Notice by clicking here.

Invicro is an equal opportunities employer and positively encourages applications from suitably qualified and eligible candidates regardless of sex, race, disability, age, sexual orientation, gender reassignment, religion or belief, marital status, or pregnancy and maternity.

Imanova Limited, company registered in England and Wales, with registration number 07516277, trading as Invicro.

 

Senior Imaging Scientist

Applications are invited for a Senior Imaging Scientist position to work within the Discovery Research (DR) group based in London.  We are seeking a Senior Imaging Scientist to design and facilitate the execution and analysis of preclinical imaging studies as well as drive new business opportunities with existing and potential Sponsors. The individual should enjoy challenging and analytical work and be motivated by the idea that together we can accomplish great things and make a positive contribution to society through our mission.

The Role

The Senior Imaging Scientist is expected to design and facilitate the execution and analysis of preclinical imaging studies within the DR group and will also play a leading role in business development activities. The ideal candidate will have experience with pre-clinical in vivo imaging techniques including understanding of theory, familiarity with data acquisition and analysis techniques, and experience in quality control and presentation of such data. They will be expected to plan, execute and manage preclinical imaging studies across various therapeutic areas and modalities, in addition to providing guidance and support for analysis of data.

The Candidate

Can demonstrate the ability to manage multiple projects at once. The candidate must be able to work quickly and accurately and pay strict attention to detail. They must be adaptable and capable of working and leading in a team environment. In addition, they must be able to professionally and confidently interact with customers and subcontractors, as well as prepare and deliver written and oral summaries of work. They will be highly motivated and able to deliver to defined timelines, in collaboration with colleagues from the preclinical sciences and image analysis groups.

Key Duties:

  • Manage the design, execution, analysis and reporting of pre-clinical discovery research studies whilst following the DR study workflows and ensuring collected and reported data is of high standard.
  • Be the sponsor facing scientist with the responsibilities of updating the sponsor during protocol development, during key study milestones, and presenting the results.
  • As the study director on multiple projects you are ultimately responsible for:
  • All internal and external study related communications.
  • Creating and maintaining an open and supportive internal team environment.
  • Sufficient knowledge on the disease of interest, its basic biology and how the specific study fits within that field to engage in discussions with sponsor
  • The integrity and quality of the data shared to the sponsor.
  • Support execution of pre-clinical imaging studies across various therapeutic areas
  • Support fellow Imaging Scientists in your key areas of expertise
  • Interface with business development, sponsors, study managers, and laboratory staff to manage all aspects of study management from proposal to final report
  • Author and review technical documents including study protocols, final reports, abstracts/manuscripts/white papers, etc.
  • Represent Invicro externally in a professional manner
  • Drive new business development opportunities

To be considered for this position, you will have:

  • Scientific/technical PhD with appropriate industry experience or Scientific/technical Masters with appropriate industry experience. PhD or MS in a relevant field (e.g. engineering, physics, chemistry or biology)
  • Significant experience with small molecule radiochemistry and/or radio- or fluorescent labeling of proteins and/or MRI, PET, SPECT, CT, or other relevant imaging modality required
  • Experience with the application of molecular imaging to study drug effects, biodistribution, and target engagement
  • Superior skills related to teamwork, multi-tasking, and time/project management
  • Ability to work quickly with strict attention to detail
  • Ability to demonstrate adaptability and past leadership experience in a team environment
  • Ability to interact professionally and confidentially with customers and subcontractors
  • Ability to prepare and deliver written and oral scientific summaries of work
  • Excellent communication skills
  • To apply for this position please forward your CV and a covering letter detailing your relevant experience to HR at recruitment@invicro.co.uk.

We ensure compliance with Data Protection laws and you can find our Privacy Notice by clicking here.

Invicro is an equal opportunities employer and positively encourages applications from suitably qualified and eligible candidates regardless of sex, race, disability, age, sexual orientation, gender reassignment, religion or belief, marital status, or pregnancy and maternity.

Imanova Limited, company registered in England and Wales, with registration number 07516277, trading as Invicro.

Clinical Project Manager

This is an exciting role for a Clinical Project Manager to join a dynamic Clinical Applications team at Invicro in London.

The role:

The Clinical Project Manager will manage (including the administration, maintenance and coordination of) the logistical aspects of clinical studies at Invicro conducted in compliance with Good Clinical Practice (GCP), Good Manufacturing Practice (GMP) and relevant Standard Operating Procedures (SOPs).

The successful candidate will:

  • Independently manage various study projects, programs simultaneously at Invicro from set-up through to close out to be conducted in compliance with the protocol, ICH GCP, GMP, SOP’s IRB/ethics committee and regulatory authorities’ requirements.
  • Participate in the review and compilation of documentation for submission to Ethics, ARSAC and regulatory agencies.
  • Participate in the completion of project agreements, clinical study contracts and CRO work orders.
  • Responsible for managing project specific financials (revrec, change orders, budgets)
  • Participate in meetings with investigative sites, key opinion leaders and consultants as needed.
  • Assesses the operational feasibility of studies and recommends execution and risk mitigation plans.
  • Manage Invicro’s project tracking tools to ensure that information is accurate and current.
  • Serve as back-up to project managers and take on individual project assignments as necessary to support the business

The successful candidate will have:

  • A degree or equivalent qualification in health sciences, nursing or pharmacy or related field
  • Direct experience and in depth understanding of requirements for conducting clinical studies within early phase clinical drug development, including issues required to support data for human experiments, study design, study conduct, regulatory, technical and logistical issues.
  • Experience of setting up clinical trials to ICH GCP, preferably obtained in industry, managing the execution phases as well tracking progress.
  • Advanced level MS Excel, PowerPoint, Word; minimum of intermediate rest of MS Office suite.
  • Good problem solving skills
  • Excellent attention to detail
  • The ability to work well under pressure
  • Excellent team working skills
  • To apply for this position please forward your CV and a covering letter detailing your relevant experience to HR at recruitment@invicro.co.uk.

We ensure compliance with Data Protection laws and you can find our Privacy Notice by clicking here.

Invicro is an equal opportunities employer and positively encourages applications from suitably qualified and eligible candidates regardless of sex, race, disability, age, sexual orientation, gender reassignment, religion or belief, marital status, or pregnancy and maternity.

Imanova Limited, company registered in England and Wales, with registration number 07516277, trading as Invicro.