The radioactivity concentration measured during a PET/SPECT exam can be related to the underlying physiological processes by using appropriate tracer kinetic modeling techniques. The identification of the correct quantification approach is fundamental to derive an accurate description of the biological processes. Kinetic analysis allows quantitative functional imaging of a variety of physiological parameters such as blood flow, rate of glucose consumption or amount of binding of the tracer to specific receptors, enzymes, misfolded proteins and more, depending upon the tracer in use.
At Invicro we support preclinical discovery and early-phase translational studies quantitate biological process through tracer kinetic analysis of PET and SPECT data.
